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Panoramic Digital Images (Panoptiq) for Cytopathology Screening and Interpretation

Liron Pantanowitz, Jacqueline Cuda, Juan Xing, Ishtiaque Ahmed, Anil Parwani, Sara Monaco

Whole slide imaging in cytology is limited when glass slides are scanned without z-stacks for focusing. The Panoptiq™ imaging system is a novel technology that allows users to create digital files that combine low-power panoramic images with regions of interest that are imaged using high-power z-stacks. This study determines the utility of Panoptiq for cytopathology screening and interpretation.

Comparison of Different Modalities for Reading 30 Cytology slides

  • 10 ThinPrep Pap tests, 10 FNA and 5 fluids comprised of smears, cytospins and cell blocks were digitized.

  • Panoptiq showed equivalent adequacy concordance, diagnostic concordance and confidence levelscompared to the traditional light microscope1

1 Pantanowitz L, Cuda J, Xing J, Ahmed I, Parwani AV, Monaco SE. Panoramic digital images (Panoptiq) for cytopathology screening and interpretation. J Am Soc Cytopathol. 2015;4:S66–7

Evaluation of Panoramic Digital Images Using Panoptiq for Frozen Section Diagnosis

Dinesh Pradhan, Sara E. Monaco, Anil V. Parwani, Ishtiaque Ahmed, Liron Pantanowitz

Twenty randomly selected genitourinary pathology frozen section cases were evaluated using conventional light microscopy and digital slides created using Panoptiq™ and Aperio. Three pathologists were asked to render diagnoses and rate the image quality and their diagnostic confidence for each modality. The aim of this study was to determine the utility of Panoptiq™ for frozen section telepathology.

Comparison of Different Modalities for Reading Pathology Slides

Based on image quality and diagnostic confidence, Panoptiq showed equivalent or higher satisfactory and confidence levels compared to the traditional light microscope.2

2 Pradhan D, Monaco SE, Parwani AV, Ahmed I, Duboy J, Pantanowitz L. Evaluation of panoramic digital images using Panoptiq for frozen section diagnosis. J Pathol Inform 2016; 7:26.

© 2019 ViewsIQ Inc. All rights reserved.

Panoptiq is for research use only. Not intended for diagnostic use.

European Patent 2740104. U.S. Patent 9,224,063. Canadian Patent 2,843,772. Japanese Patent 6112624

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